Unexplained weight loss Weight loss that seems unexplainable at first glance is a common consequence of a cancer process and in some cases even the first sign of an undiagnosed tumor. Weight loss in cancer patients can have many causes. In many cases it will be reversible and has nothing to do with the metabolic imbalance of 'true' cachexia. For example, a growth can obstruct the passage of the throat, mouth or esophagus in such a way that swallowing or eating is painful or difficult, which will eventually also lead to weight loss. Removing the tumor can offer a solution in those cases.
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